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Peter Naredi

Professor/ chief physician

Peter Naredi
Professor/ chief physician
+46 31-342 8345

Postal Address: Sahlgrenska universitetssjukhuset, 41345 Göteborg
Visiting Address: Blå stråket 5, vån 5, SU/Sahlgrenska , 41345 Göteborg

Department of Surgery at Institute of Clinical Sciences (More Information)
Sahlgrenska Universitetssjukhuset
413 45 Göteborg
Visiting Address: Blå stråket 5, vån 3 SU/Sahlgrenska , 413 45 Göteborg

About Peter Naredi


Head of the Institute of Clinical Sciences and Professor of Surgery, Sahlgrenska Academy, University of Gothenburg and Sahlgrenska University Hospital

Clinicaly I work as a cancer surgeon with special focus on the upper gastrointestinal tract and the liver.

Below are some of the projects I'm involved in right now. I am also included in an international network for the treatment of colorectal liver metastases.

1 Multidisciplinary treatment with surgery and chemotherapy of liver metastases from colorectal cancer

Cancer of the colon and rectum is common and almost half of the patients have or will have metastases (metastases) in the liver. When the spread is limited to the liver removal of liver metastases can be curative. Therefore it is important to detect liver metastases and evaluate the role of controls after the operation of the primary cancer.

The purpuse of our resarch is to find more patients that can be treated with a curative intention for liver metastases from colorectal cancer. We also want to improve chemotherapy by counteracting the resistance which tumors have or develop during treatment. We analyze the diagnostics of liver metastases, treatment decisions and outcomes of treatments. In the worm C. elegans, we are studying how to best combine targeted drugs and chemotherapy. In C.elegans, we investigate how to inhibit the function of the protein ASNA1 and thus make cancer cells more sensitive to chemotherapy. Read more on the Cancer Society's website.

2 The impact of host dependent factors and tumour interaction on survival for patients with Hepatocellular carcinoma
Patients diagnosed with hepatocellular carcinoma (HCC) often have a poor prognosis and the five-year survival rates are among the worst among tumor types, about 10 per cent. If the patients tumour is not to advanced, liver transplantation is a treatment option.
Today the development of the HCC is ruled by underlying factors, which makes it important to investigate individual specific characteristics in relation to the treatment effects. Currently used selection criteria may exclude some patients who would have survived with a liver transplantation. By exploring new and hopefully more refined and specific diagnostic instruments, we hope to expand the criteria for liver transplantation and also to identify those patients for whom palliative treatment is the best option.

3a Combat malignant melanoma on two fronts
More and more people are affected by cancer. In this project we will investigate how the disease arises and search for new drug targets - processes or mechanisms that may be affected by medication. We will study the disease in transgenic mice, and in mice bearing human tumours. The treatment will become more individualized and patients can receive proper treatment while unnecessary medication is avoided. The goal is new life-saving drugs.  Read more at the webbsait of Knut och Alice Wallenbergsstiftelsen

3b When metastases of malignant melanoma are localized to a limb or in the liver they can be treated with isolated hyperthermic perfusion of the cytotoxic drug melphalan. In a perfusion system high doses of chemotherapy drugs are given locally with less harm to the patient. How the effects of this treatment affects the body's own immune mechanisms are poorly studied. One hypothesis that we study is that it induces immunogenic cell death and activation of the immune system.

Team members within the research groups
• Gautam Kao
• Eva Philipsson
• Peter Scherman
• Dorota Raj
• Magnus Rizell
• Malin Sternby Eilard
• Jonas Nilsson
• Anna Martner
• Per Lindner
• Roger Olofsson

Financiers of the projects
• Cancerfonden
• BioCare
• ALF-projektmedel Västra Götaland
• Knut och Alice Wallenbergs stiftelsen (Martin Bergö huvudsökande)
• Sahlgrenska akademin

Main supervisor
• Malin Sternby Eilard
• Junko Johannsson

Interview in the media
Intervju Cancer World - Peter Naredi: a “can do” leader for Europe's cancer surgeons
Intervju MedScape inför 2015 års ECC-konferens med tema - “Att förstärka de multidiciplinära teamen inom cancervården
Intervju Akademiliv 2013 -En cancerkirurg med framtidstro
eCancer - Prof Naredi talks to ecancertv at ECC 2015 about the use of surgery in synchronous oligometastatic disease.

• Past President-elect, ECCO (European cancer organisation)
Past president at The European Society of Surgical Oncology ESSO 2011

Honorary Member
• European Society for Therapeutic Radiology and Oncology (ESTRO). 2012
• Society of Italian Surgical Oncology (SICO). 2012
Svensk kirurgisk förening. 2012
Hellenic society of Surgical Oncology. 2013
BASO – the organisation for Cancer Surgery, UK. 2015

Latest publications

The requirements of a specialist breast centre
L. Biganzoli, F. Cardoso, M. Beishon, D. Cameron, L. Cataliotti et al.
Breast, Journal article 2020
Journal article

ECCO Essential Requirements for Quality Cancer Care: Prostate cancer
M. Brausi, P. Hoskin, E. Andritsch, I. Banks, M. Beishon et al.
Critical Reviews in Oncology Hematology, Journal article 2020
Journal article

Moonshot or groundshot: addressing Europe's cancer challenge through a patient-focused, data-enabled lens.
Mark Lawler, Peter Naredi, Tanja Cufer, Ian Banks, Yolande Lievens et al.
The Lancet. Oncology, Journal article 2019
Journal article

Prognostic factors for survival in stage IV rectal cancer: A Swedish nationwide case–control study
K. Afshari, A. Chabok, Peter Naredi, K. Smedh, M. Nikberg
Surgical Oncology, Journal article 2019
Journal article

Centers of excellence or excellence networks: The surgical challenge and quality issues in rare cancers
S. Sandrucci, Peter Naredi, S. Bonvalot
European Journal of Surgical Oncology, Journal article 2019
Journal article

Toward a Consensus on Centralization in Surgery.
René Vonlanthen, Peter Lodge, Jeffrey S Barkun, Olivier Farges, Xavier Rogiers et al.
Annals of surgery, Journal article 2018
Journal article

Showing 31 - 40 of 160


Circulating carnosine dipeptidase 1 associates with weight loss and poor prognosis in gastrointestinal cancer.
Peter Arner, Frauke Henjes, Jochen M Schwenk, Spyros Darmanis, Ingrid Dahlman et al.
PloS one, Journal article 2015
Journal article

The future of trials in surgical oncology
Peter Naredi, M. P. La Quaglia
Nature Reviews Clinical Oncology, Journal article 2015
Journal article

Trends in cutaneous malignant melanoma in Sweden 1997-2011: Thinner tumours and improved survival among men.
J Lyth, Henry Eriksson, J Hansson, C Ingvar, M Jansson et al.
The British journal of dermatology, Journal article 2015
Journal article

Combining conventional and stroma-derived tumour markers in pancreatic ductal adenocarcinoma.
Oskar Franklin, Daniel Öhlund, Christina Lundin, Mikael Öman, Peter Naredi et al.
Cancer biomarkers : section A of Disease markers, Journal article 2015
Journal article

Protection against cold in prehospital care: wet clothing removal or addition of a vapor barrier.
Otto Henriksson, Peter J Lundgren, Kalev Kuklane, Ingvar Holmér, Gordon G Giesbrecht et al.
Wilderness & environmental medicine, Journal article 2015
Journal article


Interaction between the anticancer drug cisplatin and the copper chaperone Atox1 in human melanoma cells
M. E. Palm-Espling, C. Lundin, E. Björn, Peter Naredi, P. Wittung-Stafshede
Protein Peptide Letters, Journal article 2014
Journal article

Experts reviews of the multidisciplinary consensus conference colon and rectal cancer 2012: Science, opinions and experiences from the experts of surgery.
C J H Van de Velde, P G Boelens, P J Tanis, E Espin, P Mroczkowski et al.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, Journal article 2014
Journal article

Validity and reliability of the Cold Discomfort Scale: a subjective judgement scale for the assessment of patient thermal state in a cold environment.
Peter Lundgren, Otto Henriksson, Kalev Kuklane, Ingvar Holmér, Peter Naredi et al.
Journal of clinical monitoring and computing, Journal article 2014
Journal article

Showing 31 - 40 of 160

Page Manager: Katarina Olinder Eriksson|Last update: 3/7/2013

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